No Carrier Necessary: This Drug Delivers Itself - The problem of efficiently delivering drugs, especially those that are hydrophobic or water-repellant, to tumors or other disease sites has long challenged scientists to develop innovative delivery systems that keep these drugs intact until reaching their targets. April 19, 2007

Heart Pump Design Could Give Patients New Hope - A new counter-flow heart pump being developed by Queensland University of Technology has the potential to revolutionize future designs of the mechanical heart. April 17, 2007

Breast Cancer Treatment Heats Up - In the Journal of Nuclear Medicine, researchers demonstrate that miniscule bioprobes could be produced and used with molecularly targeted therapeutic heat to kill malignant breast cancer cells without damaging nearby healthy tissue. April 16, 2007

Chlamydia Vaccine A Step Closer To Reality - Scientists at Queensland University of Technology are one step closer to developing a world-first vaccine to protect women against contracting the most common sexually-transmitted disease, Chlamydia. April 13, 2007

New Direction For Pancreas Cell Regeneration - Replacing faulty or missing cells with new insulin-making cells has been the object of diabetes research for the last decade. April 12, 2007

Eat Well, Get Fit, Stop Smoking - Prevent Cancer - If you wanted to start today to reduce your chances of getting cancer, what would you have to do? Lose excess weight, get more exercise, eat a healthy diet and quit smoking. April 11, 2007

'Bone Quality' Is An Empty Term, Say Researchers - The idea of "bone quality" is now widely used by physicians to predict which patients are at risk of fractures, but the idea has "major conceptual flaws" argues a team of researchers from Tampere, Finland in PLoS Medicine. April 10, 2007

Scientists Decode Genome Of Oral Pathogen - Virginia Commonwealth University researchers have decoded the genome of a bacteria normally present in the healthy human mouth that can cause a deadly heart infection if it enters the bloodstream. April 9, 2007

Tiny Molecule Controls Stress-induced Heart Disease - A tiny snippet of RNA, a chemical cousin of DNA, controls damage to the heart under several types of stress, researchers at UT Southwestern Medical Center have found. April 6, 2007

Bioengineer Advances Survival, Promise Of Adult Stem Cells - MIT researchers have developed a technique to encourage the survival and growth of adult stem cells, a step that could help realize the therapeutic potential of such cells. April 5, 2007

Smokers Make Poorer Workers - Smokers perform worse at work than non-smokers, finds a study of US navy female service members published in Tobacco Control. April 4, 2007

Diet Study Tips Scale In Favor Of Atkins Plan - The case for low-carbohydrate diets is gaining weight. Researchers at the Stanford University School of Medicine have completed the largest and longest-ever comparison of four popular diets, and the lowest-carbohydrate Atkins diet came out on top. April 3, 2007

Handheld Instrument Assesses Dental Disease In Minutes - Who would have guessed that when the Star Trek medical diagnostic tool known as the tricorder makes its appearance in real life, the first user might be ... your dentist. April 2, 2007

How Estrogen Protects Bones - Researchers at the University at Buffalo have described a novel pathway by which estradiol, the primary estrogen in humans, aids in maintaining bone density, a function critical to avoiding osteoporosis. March 30, 2007

Study Reveals Depressed Elderly Risk Early Death - Depression in elderly people is causing early mortality, a University of Liverpool study has found. March 29, 2007

Estrogen Interferes With Immune Surveillance In Breast Cancer - Estrogen is known to enhance the growth and migration of breast cancer cells. Now researchers at the University of Illinois at Urbana-Champaign have found that estrogen also can shield breast cancer cells from immune cells. March 28, 2007

Diet Study Tips Scale In Favor Of Atkins Plan - The case for low-carbohydrate diets is gaining weight. Researchers at the Stanford University School of Medicine have completed the largest and longest-ever comparison of four popular diets, and the lowest-carbohydrate Atkins diet came out on top. March 27, 2007

Biodegradable Implant Holds Promise As Ovarian Cancer Treatment - A collaborative effort between researchers at the Leslie Dan Faculty of Pharmacy has resulted in an advanced drug delivery system for the treatment of ovarian cancer. March 26, 2007

Low-pitch Treatment Alleviates Ringing Sound Of Tinnitus - For those who pumped up the volume one too many times, UC Irvine researchers may have found a treatment for the hearing damage loud music can cause. March 23, 2007

Rats On A Road Trip Reveal Pollution-heart Disease Risk - Rats that rode in a truck on the New York State Thruway between Rochester and Buffalo and were exposed to the same highway pollution that motorists encounter, showed a drop in heart rate and effects on the autonomic nervous system. March 22, 2007

Exploring The Molecular Origin Of Blood Clot Flexibility - How do blood clots maintain that precise balance of stiffness for wound healing and flexibility to go with the flow? March 21, 2007

Take More Breaks To Avoid Back Injury At Work - Workers who lift for a living need to take longer or more frequent breaks than they now do to avoid back injury, according to a new study at Ohio State University. March 20, 2007

How Some Molecules Inhibit Growth Of Lung Cancer Cells - By mapping the interlocking structures of small molecules and mutated protein "receptors" in non-small cell lung cancer (NSCLC) cells, scientists at Dana-Farber Cancer Institute and their colleagues have energized efforts to design molecules that mesh with these receptors ... March 19, 2007

Is Exercise Really Good For Heart Failure Patients? - Cardiologists at Wake Forest University Baptist Medical Center are helping to lead a large international study involving 83 other sites that will test 3,000 patients in an effort to determine whether exercise really is good for heart failure patients. March 16, 2007

Ovarian Cancer May Mimic Fallopian Tube Formation - A new study suggests that ovarian cancer cells form by hijacking a developmental genetic process normally used to form fallopian tubes. March 15, 2007

Artificial Retina Could Help Blind Regain Partial Sight - Patients who have gone blind are a step closer to perhaps one day regaining some of their sight. March 14, 2007

New HIV Test May Predict Drug Resistance - Researchers at Duke University Medical Center have developed a highly sensitive test for identifying which drug-resistant strains of HIV are harbored in a patient's bloodstream. March 13, 2007

Marine Moss Reveals Clues To Anti-cancer Compound - An Oregon Health & Science University researcher believes the discovery of a gene cluster from a bacterium that protects a moss-like marine invertebrate from predators may be the first step toward engineering cancer-fighting drugs. March 12, 2007

New Hope For People With Advanced Breast Cancer - A surprising discovery by Queen’s University researchers that happened when their work took an unexpected turn may help women with advanced breast cancer respond better to conventional drug treatments. March 9, 2007

HIV Protein Enlisted To Help Kill Cancer Cells - Cancer cells are sick, but they keep growing because they don't react to internal signals urging them to die. Now researchers at Washington University School of Medicine in St. Louis have found an efficient way to get a messenger into cancer cells that forces them to respond to death signals. March 8, 2007

Discovery Of Chemical Profiles For Infectious Diarrhea - Academics have found, for the first time, smells from healthy feces and people with infectious diarrhea differ significantly in their chemical composition and could be used to diagnose quickly diseases such as Clostridium difficile (C. Diff.). March 7, 2007

Cancer Treatment Targets Tumor Blood Supply In Patients - A clinical trial has for the first time proven that an antibody called J591 specifically targets an antigen found in high amounts on both prostate tumors and on blood vessels of all solid tumors. March 6, 2007

New Technology Removes Viruses From Drinking Water - University of Delaware researchers have developed an inexpensive, nonchlorine-based technology that can remove harmful microorganisms, including viruses, from drinking water. March 5, 2007

Researcher Placing Eye Implants In Cats To Help Humans See - In "Star Trek: The Next Generation," Geordi La Forge is a blind character who can see through the assistance of special implants in his eyes. While the Star Trek character "lives" in the 24th century, people living in the 21st century may not have to wait that long for the illuminating technology. March 2, 2007

Molecular Link Between Inflammation And Cancer Discovered - A team led by biochemists at the University of California, San Diego has found what could be a long-elusive mechanism through which inflammation can promote cancer. March 1, 2007

Fetal Heart-cell Enzyme Important In Onset Of Heart Failure - In almost all forms of heart failure, the heart begins to express genes that are normally only expressed in the fetal heart. Researchers have known for years that this fetal-gene reactivation happens, yet not what regulates it. February 28, 2007

Those Who Once Were Blind Can Learn To See - How does the human brain "learn" to see? If the brain is deprived of visual input early in life, can it later learn to see at all? February 27, 2007

Caffeine May Prevent Heart Disease Death In Elderly - Habitual intake of caffeinated beverages provides protection against heart disease mortality in the elderly, say researchers at SUNY Downstate Medical Center and Brooklyn College. February 26, 2007

New Test For Most Virulent HPV Strains Under Study - A test for the two strains of human papillomavirus responsible for most cervical cancers is under study. February 23, 2007

Body Composition Device Facilitates Infant Studies - The accuracy of a new machine for estimating the body composition of infants has been demonstrated in a two-year study by scientists at the U.S. Department of Agriculture (USDA)-funded Children's Nutrition Research Center (CNRC) in Houston, Texas. February 22, 2007

Should Smokers Be Refused Surgery? - Last year a primary care trust announced it would take smokers off waiting lists for surgery in an attempt to contain costs. In this week's British Medical Journal, two experts go head to head over whether smokers should be refused surgery. February 19, 2007

Berry Compound Thwarts Enzyme Linked To Cancer - Recent research by Agricultural Research Service (ARS) scientists and cooperators has fortified the standing of pterostilbene, a berry and grape compound cited for its health benefits, as a cancer inhibitor. February 15, 2007

First Evidence Of Stem Cells In Pancreatic Tumors - University of Michigan Comprehensive Cancer Center researchers have discovered the small number of cells in pancreatic cancer that are capable of fueling the tumor's growth. February 14, 2007

Immune System Cells Linked To Heart Failure - The immune system and, more specifically, cells recruited from it are key players in the muscle dysfunction that results in some forms of heart failure, said Baylor College of Medicine researchers in a report that appears online in the Proceedings of the National Academy of Sciences. February 13, 2007

Woven Scaffolds Could Improve Cartilage Repair - Using a unique weaving machine of their design, Duke University Medical Center researchers have created a three-dimensional fabric "scaffold" that could greatly improve the ability of physicians to repair damaged joints with the patient's own stem cells. February 12, 2007

Fighting Influenza And Company With 40,000 Blood Samples - Four million people die every year from respiratory diseases such as viral influenza. For elderly people in particular, an infection can be dangerous. What is more, the flu vaccine is not as effective with this risk group as it is with younger people. February 9, 2007

Using Nano-magnets To Enhance Medical Imaging - Nanoscale magnets in the form of iron-containing molecules might be used to improve the contrast between healthy and diseased tissue in magnetic resonance imaging (MRI). February 8, 2007

Researchers Urge Monitoring Of Bone Health During Chemotherapy - In laboratory tests on mice, researchers found that a medication often used to reduce toxic side effects of chemotherapy induced bone loss and helped tumors grow in bone. February 7, 2007

Reactivated Gene Shrinks Tumors - Many cancers arise due to defects in genes that normally suppress tumor growth. Now, for the first time, MIT researchers have shown that re-activating one of those genes in mice can cause tumors to shrink or disappear. February 6, 2007

Carbon Monoxide Protects Lung Cells Against Oxygen-induced Damage - Researchers at the University of Pittsburgh have demonstrated that low-dose carbon monoxide administered in conjunction with oxygen therapy markedly inhibits oxygen-induced damage to lung cells. February 2, 2007

Seven Things To Know About Preventing, Treating Winter Laryn - With most cases of viral laryngitis occurring during the winter cold and flu season, a vocal health expert at the University of Michigan Health System is offering tips for preventing and treating the inflammation of the voice box. February 1, 2007

'Beavertail' Surgery Helps Tongue Cancer Patients - A new surgical technique pioneered at the University of Alberta has given back the ability to swallow to patients with tongue cancer. January 31, 2007

'Shape-Memory' Materials May Soon Aid Orthopedic Surgery - An early stage medical-materials company based at the Georgia Institute of Technology is developing devices that may soon improve the treatment of human orthopedic conditions. January 30, 2007

Small Molecule Offers Big Hope Against Cancer - DCA is an odourless, colourless, inexpensive, relatively non-toxic, small molecule. And researchers at the University of Alberta believe it may soon be used as an effective treatment for many forms of cancer. January 29, 2007

New Target For Treatment Of Breast Cancer - The active ingredient in a drug currently being tested to treat rheumatoid arthritis might also one day serve as an effective means of treating one of the deadliest forms of breast cancer. January 27, 2007

New Genomic Tool Makes Connections Between Drugs And Human Disease - In three papers appearing in Science and Cancer Cell, Broad researchers describe the “Connectivity Map” and its scientific applications to cancer and other diseases. January 26, 2007

Cracking Open The Black Box Of Autoimmune Disease - Autoimmune diseases such as type 1 diabetes, lupus and rheumatoid arthritis occur when the immune system fails to regulate itself. January 25, 2007

Cancer-killing Invention Also Harvests Stem Cells - Associate Professor Michael King of the University of Rochester Biomedical Engineering Department has invented a device that filters the blood for cancer and stem cells. When he captures cancer cells, he kills them. January 24, 2007

Hybrid Molecule Causes Cancer Cells To Self-destruct - By joining a sugar to a short-chain fatty acid compound, Johns Hopkins researchers have developed a two-pronged molecular weapon that kills cancer cells in lab tests. January 23, 2007

Molecular Anatomy Of Influenza Virus Detailed - Scientists at the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS), part of the National Institutes of Health in Bethesda, Md., and colleagues at the University of Virginia in Charlottesville have succeeded in imaging, in unprecedented detail, the virus that causes influenza. January 22, 2007

Can Engineered Immune Cells Stop AIDS? - Twenty years after its introduction, gene therapy still holds great promise as a way to harness the insidious power of viruses such as human immunodeficiency syndrome (HIV). January 21, 2007

Inflammatory Genes Linked To Salt-sensitive Hypertension - One key to your high blood pressure might just be your inflammatory genes. It may sound odd but mounting evidence suggests that inflammation, a part of the immune response implicated in diseases such as cancer ... January 20, 2007

Sacking Cancer Stem Cells - Scientists have found the Achilles' heel of cells that jump start tumor growth. According to a new study, these "cancer stem cells" reside in blood vessels. January 19, 2007

Napoleon's Mysterious Death Unmasked - A new investigation into Napoleon Bonaparte’s cause of death might finally put to rest nearly 200 years of lingering mysteries about the illness that killed the French emperor during his island exile. January 18, 2007

Promising For Breast Cancer Treatment - Worldwide, cancer persists as one of the most important diseases that affect the human being. January 17, 2007

Mutant Mouse Provides Insights Into Breast Cancer - By discovering a mutant mouse that is highly susceptible to mammary tumors, Cornell researchers have found a novel potential link between genetic defects in DNA replication (copying) and breast cancer. January 16, 2007

First Familial Pancreatic Cancer Gene Identified - Pancreatic cancer is relatively rare but deadly; most patients die within a year of diagnosis, and it is the fourth leading cause of cancer deaths in the US. At least 10% of pancreatic cancers are thought to be familial, i.e., caused by inherited genetic mutations. January 15, 2007

Exercise When Young May Reduce Risk Of Fractures Later In Life - Running and jumping during childhood is more than child's play; it provides lifelong benefits for future bone health and appears to reduce the risk of fractures later in life. January 14, 2007

Olive Oil Emulsion Helps With Problem Heart Arteries - An emulsion of olive oil, egg yolk and glycerine might be just the recipe to keep heart patients away from the operating room and cardiac bypass surgery. January 13, 2007

Best Treatment For Narrowed Kidney Arteries? - Whether reopening narrowed kidney arteries benefits patients is a $1.7 billion question a North American study hopes to answer. January 12, 2007

Protection Against Cancer May Begin During Pregnancy - There may be another reason for pregnant and nursing women to eat a nutritious diet that includes generous amounts of cruciferous vegetables like broccoli and cabbage ... January 11, 2007

Anthrax Attack Posed Greater Potential Threat Than Thought - A new study shows that more people were at risk of anthrax infection in the Oct. 2001 attack on U.S. Sen. Tom Daschle's office than previously known. January 10, 2007

Smoking Worsens Knee Osteoarthritis - New findings from a study led by a Mayo Clinic rheumatologist indicate that men with knee osteoarthritis who smoke experience greater cartilage loss and more severe pain than men who do not smoke. January 9, 2007

Obesity Linked To Ratio Of Gut Microbes - A link between obesity and the microbial communities living in our guts is suggested by new research at Washington University School of Medicine in St. Louis. January 8, 2007

Research Yields New Insights Into The Cause Of Diabetes - The cause of insulin-dependent, permanent, diabetes in newborn babies may be a deficiency in the enzyme Pancreatic Endoplasmic Reticulum Kinase (PERK) during a critical period of development before birth. January 7, 2007

Healthy Potato Chips: A Trans Fat Oil With Health Benefits - For plenty of good reasons, the term "trans fat" leaves a bad taste in the mouths of health-conscious consumers. Typically, trans fatty acids are bad for health, but scientists at the University of Arkansas have coaxed out significant health benefits by ... January 6, 2007

What Makes Somebody A Morning Person Or A Night Owl? - There is a strong genetic component determining whether a person is an evening or a morning type in their activity times, said Penn State psychology professor Frederick Brown. January 5, 2007

Molecular 'On/Off Switch' Controls Immune Defenses Against Viruses - Much like flipping a light switch, the hepatitis C virus turns on human immune defenses upon entering the body but also turns off those defenses by manipulating interaction of key cellular proteins, UT Southwestern Medical Center researchers have found. January 4, 2007

Pro-vitamin E Shown To Be Active Against Breast Cancer Cells - A precursor of vitamin E has been shown to be effective against breast cancer cell lines which over-express human epidermal growth factor receptor (HER2). January 3, 2007

Nanoparticle Implant Measures Tumor Growth, Treatment - A tiny implant now being developed at MIT could one day help doctors rapidly monitor the growth of tumors and the progress of chemotherapy in cancer patients. January 2, 2007

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